Graduate in Biology, Biochemistry, University Nijmegen, The Netherlands, 1977. Doctor of Philosophy, University Nijmegen, The Netherlands, 1982.
Academy researcher department biochemistry Faculty of Medicine, University of Nijmegen, The Netherlands, 1977-1982. Researcher department biochemistry Netherlands Cancer Institute, Amsterdam, 1982-1983. Academy researcher department of oncology Vrye University Hospital, The Netherlands, 1983-1989, head biochemistry pharmacology section department of oncology, since 1989.
Visiting researcher Edmonton, Canada, Calgary, Canada, San Diego, 1980. Senior research fellow Royal Netherlands Academy of Sciences, 1987-1992. Member science committee VII International Symposium on Purine and Pyrimidine Metabolism in Man, Bournemouth, England, 1991, vice president 4th symposium, Nymegen, The Netherlands, 1993, VIIIth International Symposium, Bloomington, Indiana, 1994, IXth International Symposium Purine Pyrimidine Metabolism in Man, Gmunden, Austria, 1997, XI meeting European Society Medical Oncology, Lyon, France, 1992.
Member science committee of winter meeting European Organization on Research and Treatment of Cancer-Pharmacology and Molecular Mechanism group meeting, Toulouse, France, 1995. Member science and organizing committee International Symposium Colorectal Cancer: from Gene to Cure, Amsterdam, 1995, organizer and president science committee, Amsterdam, 1999. Member science and organizing committee International Symposium Biliopancreatic Cancer: from Gene to Cure, Amsterdam, 1999.
Member committee European Society for the Study on Purine and Pyrimidine Metabolism in Man, vice president, since 1999.
Member Free University Council, Amsterdam, 1994-1998, member committee Education and Science. Member Dutch Society Biochemistry and Molecular Biology, Dutch Society Oncology, Purine and Pyrimidine Investigators in Netherlands (meeting organizer), Dutch Cancer Society (committee clinical and experimental therapy since 1994), American Association Cancer Research, European Organization for Research and Treatment of Cancer (pharmacology and molecular mechanisms group, council member since 1991, organizer winter meeting Amsterdam 1999, screening and pharmacology group since 1993, others), Royal Netherlands Academy of Sciences (society research-fellows, council 1990-1993, secretary 1990-1993).
Married Maria W. Delahaye, 1978. Children: Angela, Michel, Vincent.