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(This is a reproduction of a book published before 1923. T...)
This is a reproduction of a book published before 1923. This book may have occasional imperfections such as missing or blurred pages, poor pictures, errant marks, etc. that were either part of the original artifact, or were introduced by the scanning process. We believe this work is culturally important, and despite the imperfections, have elected to bring it back into print as part of our continuing commitment to the preservation of printed works worldwide. We appreciate your understanding of the imperfections in the preservation process, and hope you enjoy this valuable book. ++++ The below data was compiled from various identification fields in the bibliographic record of this title. This data is provided as an additional tool in helping to ensure edition identification: ++++ Studies In Fat Necrosis; Volume 10 Of The Decennial Publications reprint Harry Gideon Wells University of Chicago Press, 1903 Medical; General; Fat necrosis; Medical / General; Social Science / Women's Studies
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Harry Gideon Wells was born in Fair Haven, Connecticut, the second child and first son of Romanta Wells, a pharmacist and wholesale druggist, and Emma Townsend (Tuttle) Wells, daughter of a local farmer. Through his father he was descended from Thomas Welles, second governor of the Hartford Colony.
The boy attended public schools in both Fair Haven and New Haven (into which Fair Haven was absorbed), including New Haven's Hillhouse High School. During his high school years his family moved to a new residence near Yale University where their neighbors included the distinguished chemists Lafayette B. Mendel, Thomas B. Osborne, and Samuel W. Johnson. Wells's contact with these men may have influenced his choice of a career. In 1892 he entered the Sheffield Scientific School at Yale with an interest in paleontology, but by his third year he had turned to biochemistry. Working under Mendel and Russell H. Chittenden, he graduated with the Ph. B. degree in 1895. He received the M. D. degree in 1898.
Family contacts played a part in the next stage in his career. The failure of his father's drug business had led the family, impressed by the wonders of the Chicago World's Fair of 1893, to move to that city, where the elder Wells bought a drugstore close to Rush Medical College. The store also housed the office of a noted surgeon, Edward W. Lee, who was associated in practice with John B. Murphy of Rush. Wells's acquaintance with these two men decided him on a medical career, and he enrolled at Rush. Although Wells served a year's internship at the Cook County Hospital, his interests lay in research rather than in medical practice, and he next obtained a fellowship to begin graduate study in pathology at the University of Chicago and to work as assistant to Ludvig Hektoen, one of his professors at Rush. At the university Wells took work in chemistry under Julius Stieglitz and carried out research on tetanus, the role of iodine in the functioning of the thyroid gland, and blastomycetic dermatitis. He received the Ph. D. in pathology in 1903 for his study of fat necrosis. He had been appointed to the medical faculty of the University of Chicago in 1901 as an associate in pathology; he was made an instructor in 1903 and assistant professor in 1904, after which he went abroad for a year's post-graduate study at the University of Berlin. There he worked with such men as Ernst Salkowski, the outstanding chemical pathologist of the era, and Emil Fischer, the great biochemist. Wells returned to Chicago in 1905 to begin a productive period of research; within a decade he had become the leading authority in the United States on the chemical aspects of pathology and immunology. His early work on fat necrosis was followed by research on tissue staining, enzyme action, degenerative processes, and pathologic calcification. He also continued his affiliation with the medical school, becoming associate professor (1909) and professor (1913) of pathology, a position he held until 1940. In 1911 Wells took on additional responsibility as the first director of the Otho S. A. Sprague Memorial Institute, established in Chicago for the study of disease and the relief of human suffering. In this position, which he also retained until 1940, he stimulated and supported research in many fields, including the chemotherapy of tuberculosis and the role of heredity in cancer. The latter investigation involved him in much debate because of the controversial theories of his associate in the work, Maud Slye. In 1917, during World War I, Wells joined an American Red Cross mission to Romania to investigate epidemics of cholera, typhoid, and typhus. The mission's work was cut short, but after the armistice Wells returned to Romania, where, under the auspices of the Red Cross and the United States Food Administration, he had responsibility for the relief of a large population and supervised the distribution of supplies from Red Cross ships. He proved an able administrator and received the Order of the Star of Romania from the royal family. Wells returned to Chicago in 1919 to resume his research. Although his major interests were in chemotherapy and immunology, he was also an outstanding tissue pathologist, and he conducted autopsy conferences at the County Hospital and at the University of Chicago. His work included studies of adrenal gland atrophy, muscle degeneration, and postoperative embolism. These investigations often kept him in the laboratory far into the night, but he found relaxation in going to late movies and in slipping into the baseball park located near the County Hospital whenever the opportunity presented itself. He was much interested in the pathology of the liver and did considerable research on experimental cirrhosis, primary carcinoma of the liver, acute yellow atrophy, and chloroform necrosis of the liver. He also worked on fat and lipoid changes in malignant tumors of the kidney. He produced papers on the chemistry of autolysis and immunity, the chemical composition of the tubercle bacillus, purine metabolism, calcification, ossification, the chemistry of proteins, anaphylaxis, and cancer in mice, the latter work being done with collaborators. Wells was an effective teacher of both medical undergraduates and postgraduates. He served as secretary (1908 - 09) and chairman (1909 - 10) of the section on pathology and physiology of the American Medical Association. He was president of the American Association of Pathologists and Bacteriologists (1919), of the American Association of Immunologists (1923), and of the American Association for Cancer Research (1915-16, 1919 - 20), and a member of various other societies, including the American Society of Biological Chemists and the American Society for Experimental Pathology. He was elected to the National Academy of Sciences in 1925. Wells's chief hobby was fishing; a major inducement in persuading him to lecture out of town was proximity to a fishing area. In the early 1930's Wells became aware of a serious cardiac condition, and though for several years he tried to continue his academic activities as head of the department of pathology, his bad health forced him to retire in 1940. He died at the age of sixty-seven at the Billings Hospital in Chicago, following surgery for carcinoma of the colon.
Wells's most notable contribution to medicine was his classic book, Chemical Pathology. First published in 1907, it remained the most authoritative work on the subject for many years, the fifth and last edition appearing in 1925. His second book, The Chemistry of Tuberculosis (1923), was written in collaboration with Lydia De Witt and Esmond R. Long. His work on protein sensitivity and anaphylaxis, in collaboration with Thomas B. Osborne, was also of great importance and culminated in The Chemical Aspects of Immunity (1924). Wells was also author or co-author of approximately 250 papers, the first, on congenital syphilis, published in 1897, the last, on seminoma, shortly before his death.
(This is a pre-1923 historical reproduction that was curat...)
(This is a reproduction of a book published before 1923. T...)
Witty, sarcastic, and enthusiastic, he made pathology a vital subject and assembled an outstanding museum of specimens designed for teaching.
On April 2, 1902, Wells married Bertha Robbins of Newington, Connecticut. Their only child was Gideon Robbins.
