He entered business at age of twenty and soon obtained a responsible position in a native bank in Hankou (now Wuhan). Mr. Chou was also an organiser and manager of the King On Bank and also founder of the Tow Toong native bank in Hankou. Chou Hsing-tang joined the Sumitomo Bank as assistant compradore and in 1923 was elected a chairman of the Hankou General Chamber of Commerce.
When the Nationalist Revolutionary forces reached Hankou, he was appointed member of the Sino-Foreign Board of Directors of the Special Administrative District No. 2, (Ex-Rusaian Concession). In 1928 Mr. Chou was a chairman of the Anti-Japanese Boycott Committee in Hankou in protest against the Tsinan Incident.