Background
Klotz, Irving Myron was born on January 22, 1916 in Chicago, Illinois, United States. Son of Frank and Mollie (Nasatir) Klotz.
(A foundation for quantitative perspectives and a framewor...)
A foundation for quantitative perspectives and a framework for interpreting experimental observations. Researchers in the life sciences who are unaware of the origins of the fundamental concepts and theoretical constructs in ligand-receptor energetics may fail to recognize the hidden assumptions and premises in their interpretations of observed phenomena. This book offers a detailed exposition of these fundamentals and of the treatment of multiple equilibria in successive steps of the binding of ligands to receptors. It also describes the calculations and meanings of energetic quantities for ligand-receptor complexes. Ligand-Receptor Energetics is the only book on this topic that is both accessible to beginners and extremely useful for experienced investigators. It features numerous specific examples; tables of literature results; extensive, up-to-date thermodynamic data; graphical representations of ligand bonding concepts; and four helpful appendices. Topics covered include: * Affinities -from site, stoichiometric, and ghost-site perspectives * Facts and fantasies from graphical analyses * Numerical evaluation of stoichiometric binding constants * Affinity profiles * Thermodynamic perspectives * Forces of interaction * Molecular scenarios. This valuable supplementary text for students in all areas of the basic life sciences is also an excellent professional reference for researchers in biochemistry, molecular biology, physiology, biophysics, microbiology, neurobiology, immunology, pharmacology, endocrinology, and toxicology.
http://www.amazon.com/gp/product/0471176265/?tag=2022091-20
Klotz, Irving Myron was born on January 22, 1916 in Chicago, Illinois, United States. Son of Frank and Mollie (Nasatir) Klotz.
Bachelor of Science, University of Chicago, 1937; Doctor of Philosophy, University Chicago, 1940.
Research associate in chemistry, Northwestern University, 1940-1942; instructor, Northwestern University, 1942-1946; assistant professor, Northwestern University, 1946-1947; associate professor, Northwestern University, 1947-1950; professor, Northwestern University, 1950-1963; Morrison professor of chemistry, Northwestern University, 1963-1986; professor emeritus, Northwestern University, since 1986. Lalor fellow Marine Biological Laboratory, Woods Hole, Massachusetts, 1947-1948, corporation member, since 1947, trustee, 1957-1965.
(A foundation for quantitative perspectives and a framewor...)
(Will be shipped from US. Brand new copy.)
Fellow Royal Society Medicine, American Academy Arts and Sciences, American Association for the Advancement of Science. Member National Academy of Sciences, American Society Biochemistry and Molecular Biology, American Chemical Society (Eli Lilly award 1949, Midwest award 1970), Phi Beta Kappa, Sigma Xi, Phi Lambda Upsilon, Alpha Chi Sigma.
Married Mary Sue Hanlon, August 7, 1966. Children: Edward, Audie Jeanne, David.