Bachelor of Science in Cell Biology, McGill University, Montreal, Canada, 1972. Doctor of Philosophy in Biochemistry, Cornell University, Ithaca, New York, 1977.
Research associate in biochemistry Cornell University, 1977-1979. Assistant professor department biological chemistry Harvard Medical School, Boston, 1979-1983, associate professor department biological chemistry, 1983-1984, associate professor department genetics, 1984-1987, professor department genetics, since 1988. Associate molecular biologist Massachusetts General Hospital, 1984—1987, molecular biologist, since 1988, Alex Rich distinguished investigator department molecular biology, since 2000.
Jean Weigle lecturer University Geneva, 1994. William Rauscher memorial lecturer Rensselaer Polytechnic Institute, Troy, New York, 1995. Susan Swerling memorial lecturer Dana Farber Cancer Institute, Boston, 1997.
Proctor & Gamble lecturer University Illinois, Urbana-Champaigne, 1998. Investigator Howard Hughes Medical Institute, since 1998. Capital Science lecturer Carnegie Institution Washington, 2001.
Visiting fellow Brasenose College, Oxford University, 2005.
Fellow: New York Academy of Sciences. Member: National Academy of Sciences (Award in molecular biology 1994), American Academy Arts & Sciences.