The Hatchards bookshop there is still in business. Hatchard had a trial at the works of the printer Thomas Bensley. He then served on apprenticeship, with John Ginger of College Street, Westminster.
He later became an assistant to Thomas Payne of Mews Gate, and went into business on his own account at 173 Piccadilly, London.
Starting there in 1797, he had the largest business in the retail book trade in London after four years. In 1801 Hatchard moved from 173 Piccadilly to Number.
189–190. In 1820 that number was changed to 187.
The original shop at 173 was demolished in 1810, replaced by the Egyptian Hall. In 1817 Hatchard was taken to court in a libel case, and fined £100.
He was publisher of a Report of the African Institution, which contained a story of a whipping of a pregnant slave on Antigua, which was found to be a fabrication. lieutenant reflected on the aides of Sir James Leith, the Governor of the Leeward Islands.
Hatchard died at Clapham Common, 21 June 1849, aged 80.
Hatchard married Elizabeth Lambert in 1790. The elder son, John Hatchard, was vicar of Saint Andrew"s, Plymouth, and the second son, Thomas succeeded as head of the house of Hatchard & Son, booksellers and publishers, 187 Piccadilly. Of the two other daughters, Sophia married J. R. P. Bright, and Frances died unmarried aged 19, in 1831.