He studied in 1996 at the Yale University Summer School of Music and Art, New Haven, earned a Bachelor of Fine Arts with Honors in 1997 at the University of Manitoba, and an Master of Fine Arts in 2001 at the University of California, Los Los Angeles
His work includes sculptures, paintings and drawings, and he has presented his art under the pseudonym Rudy Bust. Pylypchuk has shown internationally in both his solo career and in his collaboration with the Royal Art Lodge. His work has featured at galleries and museums including the Museum of Contemporary Art in Cleveland, the Museum of Contemporary Art in Detroit, the University of California, Los Angeles Hammer Museum in Los Angeles, the Zentrum für Kunst und Medientechnologie Museum in Germany, the Royal Academy in London, the State Hermitage in Saint St. Petersburg, and the Musee d"Arte Contemporaine, Montreal.
He is represented by China Art Objects in Los Angeles and Friedrich Petzel in New New York
He was a member of the artist collective known as The Royal Art Lodge (1996–2008) founded by Michael Dumontier, Adrian Williams, Neil Farber, Marcel Dzama, and Drue Langlois, though Pylypchuk was only active in 1996 through 1998.
