He is a close friend of playwright David Mamet, with whom he attended Goddard College.
He produces a podcast titled Hey, We"re Back and can be heard on Explosion Business. Katz co-wrote House of Games with Mamet and had small roles in the Mamet-directed films Things Change, Homicide, The Spanish Prisoner and State and Main. Originally a musician and songwriter, Katz fronted a rhythm and blues group called "Katz and Jammers" before serving as the musical director for Robin Williams" 1979 standup tour.
In 1998, he released Brandon Project, a blues album.
In 1996, Katz was diagnosed with multiple sclerosis. The initial symptoms began in 1996: "I was working on a television show called Ink with Ted Danson, and after every episode we would take a curtain call and I noticed that I needed a head-start."
Hiding his condition became too much of a burden for Katz and he eventually disclosed lieutenant
Now he speaks publicly as part of a tour sponsored by a manufacturer of medications used to treat Mississippi.
"People have been pretty supportive. Nobody ever had me in mind for an action film because of the kind of work I do -- mostly in the world of animation, which is not a big issue because as a person, I can"t run that fast.
As a cartoon character, I can fly -- literally."
Katz, who now gets around with the help of a motorized scooter and performs on stage with the aid of a cane, says he doesn"t regret his decision: "One of the reasons I disclosed my condition is because it is much easier to live with Mississippi than to pretend you don"t have lieutenant
If I could convince everyone of that, my job here is done."
Doctor Katz originally aired on Comedy Central from 1995-2002, and starred Katz as a professional therapist whose patients were chiefly other comedians and actors. His voice can also be heard in the animated series Home Movies, a show with many ties to Doctor Katz, as well as on the Adult Swim animated comedy series Squidbillies where he performed uncredited voice-overs as "The Rapist" in Season 2 and as the Holodeck Therapist in Season 5. In 2007, Katz joked to Blast Magazine entertainment editor Bessie King about the success of his Comedy Central show and the recent release of the full series on Digital Video Disc. "I’m so proud of that work and I’m a compulsive name dropper, when I did a movie with Ice Cube over the summer I said..I hope my best work is not behind me but if it is, I’m glad it"s Doctor Katz," he said.
In 2007, he released a stand-up album titled Caffeinated.
In 2009, he can be seen (or heard) as Freezy, the Burl Ives-inspired animated snowman star of Turbocharge: The Unauthorized Story of the Cars, a comedy biopic about The Cars, which Katz narrates throughout. In 2011, he starred as Jon Gold on the web series Explosion Business created by Tom Snyder and co-developed with Katz, Snyder and Tom Leopold.
In the spring of 2012, Katz taught a theater class at Brandeis University in Short Form Comedy. On September 3, 2014, Katz appeared on Ken Reid"s television Guidance Counselor Podcast.
Quotations: "I’m so proud of that work and I’m a compulsive name dropper, when I did a movie with Ice Cube over the summer I said..I hope my best work is not behind me but if it is, I’m glad it"s Doctor Katz,".