Her brother is Luís Miguel Beleza. She is the 1st President of the Champalimaud Foundation. Leonor Beleza is a graduate of the University of Lisbon Law School, where she has also worked as an Assistant Professor.
During a distinguished professional career she has held a number of high-profile public offices.
Among other positions, she was Secretary of State of the Presidency of the Cabinet (1982-1983), Secretary of State for Social Security (1983-1985), and Minister of Health (1985-1990) in the Portuguese Government. In addition to her prominent role in public affairs Mrs Beleza has also played an active role in the private sector.
She is also a vigorous campaigner for women's rights, a cause she has supported for many years. In 2004, Leonor Beleza was appointed Chairman of the Champalimaud Foundation by the will of António Champalimaud.
In 2001, a Portugal court indicted Beleza propagating a contagious disease during her time in as Health Minister during the 1980s.
More than 100 Portuguese haemophiliacs had become infected with the Acquired Immune Deficiency Syndrome virus after receiving transfusions of contaminated plasma that had been imported and distributed by the public health service, part of the larger worldwide contaminated haemophilia blood products scandal.
Member of the Social Democratic Party, she served twice as Minister of Health in the Portuguese government. She has been elected as a Member of Parliament on several occasions and on two occasions she has served as Vice-President of the Parliament (1991-1994, 2002-2005). Leonor Beleza is currently the Chairman of the Portuguese League for People with Physical Disabilities, Chairman of the Advisory Board of the Doctorate. Pedro IV Foundation, and a member of the General Councils of the CEBI Foundation and of the Gil Foundation.