Career
Rojo del Río was born in Tula, Mexico on September 24, 1708. On 1758, he was consecrated archbishop of the Archdiocese of Manila. On May 31, 1759, the death of Governor-General Pedro Manuél de Arandía left the position vacant.
Bishop Miguel Lino de Ezpeleta of the Archdiocese of Cebu succeeded him as well as becoming acting Archbishop of Manila.
On 22 July 1759, Rojo del Río was enthroned as Archbishop of Manila. In 1761, a royal decree from Spain ruled that Rojo del Río replace Ezpeleta to become Governor-General.
Delegate Río died in office on 20 January 1764. "Albeit he had the gift of knowledge, he had no judgment, especially in matter military, to which he was hostile and negative, since this was an area outside his profession and character." This was to prove fatal during the Battle of Manila (1762).