ruler Marchioness of Montferrat
Margaret was born in Casale to William IX of Montferrat and his wife Anne of Alençon. Her mother was the third child of René, Duke of Alençon and his second wife Margaret of Lorraine, daughter of Frederick, Count of Vaudémont and Yolande of Valois-Anjou.
Margaret"s maternal grandfather died two days after the birth of Anne. Margaret"s paternal grandparents were Bonifacio III of Montferrat and Marija Brankoviç of Serbia. Margaret was the second of three children.
As Francesco was still only a minor aged eight, Margaret acted as his regent.
Guglielmo then became Duke of Mantua. Margaret lived to see three grandchildren, those of Guglielmo and Eleanor.
After Margaret"s death, five more grandchildren were born including Charles I, Duke of Mantua. Margaret died in Mantua on 28 December 1566.
In 1574, Margaret"s homeland of Montferrat became part of the Duchy of Mantua, after the death of Margaret"s son.
In Montferrat, Guglielmo was known as Guglielmo X.
