Romania was the only country in the world to allow women to pilot medical missions during the war. Drăgescu received her pilot"s license in 1935 when she was 23 years old. She became one of the few women in the world to hold a license at the time.
In 1938, with the threat of conflict growing in Europe, Drăgescu was invited to join a new, all-female aviation team which would become the White Squadron.
The other four women to join with her were Virginia Duțescu, Nadia Russo, Marina Stirbey, and Irina Burnaia. The contributions of Drăgescu and the other women of the White Squadron to the history of Romanian aviation were ignored during the country"s Communist era, but have received a more appropriate estimation in recent years, following the Romanian Revolution of 1989.
Mariana Drăgescu died on 24 March 2013, at the age of 100.