Background
Vanhoutte, Paul Michel Georges was born on November 26, 1940 in Merelbeke, Oost-Vlaanderen, Belgium. Became American Citizen, 1992. Son of Robert Edouard and Alice (Hubert) Vanhoutte.
(It is an exciting task to be the editor of the first mono...)
It is an exciting task to be the editor of the first monograph covering a new area of the biomedical sciences. Since the first report in 1980 by Robert Furchgott and colleagues (see Chapter 1) of the evidence of endothelium-dependent relaxation in isolated arteries, there are ever increasing numbers of vascular physiologists and pharmacologists who are scraping away the endothelium to look into its role in cardiovascular con trol. And the more one looks, the more one discovers. Not only is the list of substances that can induce endothelium-dependent relaxations im pressively long, but these intriguing cells can also secrete vasoconstrictor substances. The ability of the endothelium to modulate the degree of con traction of the underlying smooth muscle is an ancestral property of the blood vessel wall, illustrating the logic of nature, since the endothelial cells are located in the best possible strategic location to continuously monitor the properties (chemical or physical) of the blood. And more and more data emerge suggesting that in several cardiovascular diseases per turbations in endothelium-dependent responses are one of the early signs of the abnormal process. Thus, the importance of endothelium-dependent responses, triggered by the intellectual curiosity of one of the pioneers of vascular physiology and pharmacology, is now recognized not only by basic scientists, but also by all concerned with the cardiovascular diseases. The purpose of this monograph is to provide them with a reference work, so that they know where to start.
http://www.amazon.com/gp/product/0896031284/?tag=2022091-20
(It is an exciting task to be the editor of the first mono...)
It is an exciting task to be the editor of the first monograph covering a new area of the biomedical sciences. Since the first report in 1980 by Robert Furchgott and colleagues (see Chapter 1) of the evidence of endothelium-dependent relaxation in isolated arteries, there are ever increasing numbers of vascular physiologists and pharmacologists who are scraping away the endothelium to look into its role in cardiovascular con trol. And the more one looks, the more one discovers. Not only is the list of substances that can induce endothelium-dependent relaxations im pressively long, but these intriguing cells can also secrete vasoconstrictor substances. The ability of the endothelium to modulate the degree of con traction of the underlying smooth muscle is an ancestral property of the blood vessel wall, illustrating the logic of nature, since the endothelial cells are located in the best possible strategic location to continuously monitor the properties (chemical or physical) of the blood. And more and more data emerge suggesting that in several cardiovascular diseases per turbations in endothelium-dependent responses are one of the early signs of the abnormal process. Thus, the importance of endothelium-dependent responses, triggered by the intellectual curiosity of one of the pioneers of vascular physiology and pharmacology, is now recognized not only by basic scientists, but also by all concerned with the cardiovascular diseases. The purpose of this monograph is to provide them with a reference work, so that they know where to start.
http://www.amazon.com/gp/product/1461289394/?tag=2022091-20
biologist educator medical Pharmacologist research executive
Vanhoutte, Paul Michel Georges was born on November 26, 1940 in Merelbeke, Oost-Vlaanderen, Belgium. Became American Citizen, 1992. Son of Robert Edouard and Alice (Hubert) Vanhoutte.
Bachelor of Science magna cum laude, University Ghent, Belgium, 1961. Doctor of Medicine magna cum laude, University Ghent, Belgium, 1965. Master of Science cum laude, University Ghent, Belgium, 1970.
Doctor of Philosophy, University Antwerp, Belgium, 1973. Doctor honoris causa, State University Ghent, 2001.
Research assistant, Laboratory Normal and Pathol. Physiology, U. Gent, Belgium, 1965-1968;
first assistant, Laboratory Normal and Pathol. Physiology, U. Gent, Belgium, 1969-1971;
research assistant department physiology and biophysics, Mayo Clinic, Rochester, Minnesota, 1968-1969;
research associate, Mayo Clinic, Rochester, Minnesota, 1972-1973;
consultant department physiology and biophysics and department cardiovascular medicine, Mayo Clinic, Rochester, Minnesota, 1981-1989;
head department internal medicine Laboratory Pathophysiology, U. Antwerp, Wilrijk, Belgium, 1973-1975;
head division internal medicine Laboratory Pharmacology, U. Antwerp, Wilrijk, Belgium, 1975-1981;
director department medicine Center Experimental Therapeutics, Baylor College, Houston, 1989-1992;
vice president research, Institute de Recherches Internationales Servier, Courbevoie, France, since 1992.
Lecturer in pathophysiology National University of Rwanda, Butare, 1967. Assistant professor physiology Mayo Medical School University of Minnesota, Rochester, 1972-1973, visiting lecturer, 1974-1975, professor physiology and pharmacology, 1981-1989. Assistant lecturer physiopathology U. Antwerp, Wilrijk, 1973, lecturer in physiology and pathophysiology, 1974, lecturer in physiology Premed.
School, 1974-1977, professor pharmacology and physiology, 1975-1981. Visiting professor Polish Academy Sciences, Warsaw, 1979. Visiting faculty member Mayo Clinic and Mayo Foundation, Rochester, 1979-1980.
Ad hoc member experimental cardiovascular science study section National Institutes of Health, 1984, member program project review committee A National Heart and Lung Institute, 1988-1992, chair, 1991-1992, member reviewers research, since 1992. Professor medicine, pharmacology and physiology Baylor University, Houston, 1989-1995. Fouad A. Bashour visiting professor University Texas, Dallas, 1988.
Philip Dow lecturer Medical Augusta, Georgia, 1988. Lorenzini lecturer, Padova, Italy, 1989. Visiting professor British Heart Foundation, Royal Postgraduate Medical School, London, 1989, Royal College Physicians and Surgeons Canada, Winnipeg, 1989.
Wellcome visiting professor in basic medical science Tulane University, New Orleans, 1990. Louis B. Bishop lecturer American College Cardiology, New Orleans, 1990. ICI/Manchester (England) U.Prize lecturer, 1991.
Founders lecturer in basic science Association Academy Surgery, 1991. Pfizer visiting professor in cardiovascular medicine New York Medical College, 1992. Member of commission on autonomic nervous system International Union Physiological Sciences, since 1988.
Chairman nomenclature and drug classification commission on receptor International Union Pharmaceutical Sciences, 1989-1998, secretary- general, since 1998. Honorary.prof. Pekin U. Medical College, Beijing.
(It is an exciting task to be the editor of the first mono...)
(It is an exciting task to be the editor of the first mono...)
(Free electronic supplement: not available in print Availa...)
(Book by Shepherd, John T)
Fellow American College Angiology, American College Cardiology, American Heart Association (member stroke council, member council on high blood pressure research, medical advisory board, member council circulation), American Physiological Society (member cardiovascular section, member committee liaison for industry 1987-1991), Society Vascular Medicine and Biology. Member American Society Clinical Investigation (emeritus), American Society Pharmacology and Experimental Therapeutics, Association American Physicians, Association des Pharmacologistes (France), Belgian Society Physiology and Pharmacology, Biophysics Society, British Pharmaceutical Society, International Society Hypertension, International Society Endothelialization in Cardiovasc. Surgery (founding member), Academy Europea, Brazilian Academy Medicine (honorary), Koninklijke Academy voor Geneeskunde van Belgie (correspondent), Inter-American Society Hypertension, European biomedical Research Association (founding member), German Society Angiology (honorary), Panamerican College Endothelium (honorary), Purine Club (representative France), Serotonin Club (founder, past president), Sigma Xi.
Married Jacqueline A. Vandenberghe, April 2, 1966. Children: Valerie, Jacqueline, Paul-Robert, Alexis.