Career
He was called Don Pedro Luis. In the spring of 1456 he was named Captain-General of the Church and castellan of Sant"Angelo, in the autumn of the same year Pope made him Governor of Terni, Narni, Todi, Rieti, Orvieto, Spoleto, Foligno, Nocera, Assisi, Amelia, Civita Castellana, and Nepi, and at the beginning of 1457 the governorships of the provinces of Patrimony and Tuscany were added to these. Such rapid promotions of young relatives of the Spanish Pope Callixtus III were criticised by many older cardinals (eg Domenico Capranica) and met also with opposition of rather xenophobic Roman populace.
Particularly Orsini family opposed Borgias.
Their enmity towards them increased when Don Pedro Luis was sent to recover for the Church some fortresses kept by Orsinis, and on August 19, 1457 was appointed Prefect of Rome in succession to Antonio Orsini. lieutenant was said that Pope Callixtus III wanted to make him Emperor of Constantinople after its recovering from the Turks.
He died en route at Civitavecchia, left by almost all of his companions, being only 26 years old.