Bachelor of Science, Harvard University, 1962; Doctor of Medicine, Harvard University, 1967.
Intern, University of Chicago Hospital & Clinics, 1967-1968; research associate, National Institute of Mental Health, Bethesda, Maryland., 1968-1970; visiting fellow, University College, London, 1970-1972; assistant professor, U. Colorado Health Science, Denver, 1972-1976; associate professor, U. Colorado Health Science, 1976-1980; professor, U. Colorado Health Science, 1980-1981; Anugrah Narayan Richards professor, chairman, University of Pennsylvania, Philadelphia, 1981-1994; vice president C.N.S. Drug Discovery, Bristol-Myers Squibb, Wallingford, Connecticut, since 1995.
Medical advisory board Dysautonomia Foundation, since 1977. Lieutenant Commander United States Public Health Service, 1968-1970. Member Society Neurosci.
(membership committee, treasurer), American Heart Association (research committee), John Morgan Society (secretary-treaas. since 1988), Pennsylvania Heart Association.
Married Marlene Sirota, 1963. Children: Jeffrey, Sharon.