Background
Hollaender, Alexander was born on December 19, 1898 in Samter, Germany. Son of Heymann and Doris (Rotholz) Hollaender. came to the United States, 1921, naturalized, 1927.
(William C. Taylor Department of Genetics University of Ca...)
William C. Taylor Department of Genetics University of California Berkeley, California 94720 It is evident by now that there is a great deal of interest in exploiting the new technologies to genetically engineer new forms of plants. A purpose of this meeting is to assess the possibilities. The papers that follow are concerned with the analysis of single genes or small gene families. We will read about genes found within the nucleus, plastids, and bacteria which are responsible for agri culturally important traits. Given that these genes can be isolated by recombinant DNA techniques, there are two possible strategies for plant engineering. One involves isolating a gene from a cultivated plant, changing it in a specific way and then inserting it back into the same plant where it produces an altered gene product. An example might be changing the amino acid composition of a seed pro tein so as to make the seed a more efficient food source. A second strategy is to isolate a gene from one species and transfer it to another species where it produces a desirable feature. An example might be the transfer of a gene which encodes a more efficient pho tosynthetic enzyme from a wild relative into a cultivated species. There are three technical hurdles which must be overcome for either strategy to work. The gene of interest must be physically isolated.
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(Delbert M. Shankel Departments of }1icrobiology and Bioch...)
Delbert M. Shankel Departments of }1icrobiology and Biochemistry The University of Kansas Lawrence, Kansas 66045 Welcome to the "International Conference on Mecha. nisms of Antimutagen esis and Anticarcinogenesis. " We are delighted that so many of you have chosen to attend this first meeting on this important topic. The significance of genetic changes in cells has been recognized for many years. The seminal observations of Henri in 1914 (UV), Muller in 1927 (X-rays), and Auerbach in 1946 (chemical agents) established the fact that physical and chemical agents which may be present in our environment are capable of producing profound changes in heredity. It is now well-estab lished, of course, that such changes can result in the development of can cer, produce hereditary birth defects, alter microorganisms to cause drug resistance, or other harmful (or even beneficial) changes; it is likely that the processes of mutagenesis and the intricate balance between muta genesis and antimutagenesis are involved in aging, evolution, and other fundamental life processe8. Consequently, we hope and believe that assem bling thi. s group of scientists to share current fundamental and applied research in these areas will lead to a better understanding of these proc esses and to long-term benefits for society. As stated clearly by Garfield (4), "Almost every aspect of modern liv ing exposes us to health risks.
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Hollaender, Alexander was born on December 19, 1898 in Samter, Germany. Son of Heymann and Doris (Rotholz) Hollaender. came to the United States, 1921, naturalized, 1927.
Bachelor of Arts Wisconsin, 1929. Master of Arts, University Wisconsin, 1930. Doctor of Philosophy, University Wisconsin, 1931.
Doctor of Science honoris causa, University Wisconsin, 1969. Doctor of Science honoris causa, University Vermont, 1959. Doctor of Science honoris causa, University Leeds, England, 1962.
Doctor of Science honoris causa, Marquette University, 1967. Doctor of Medicine honoris cause, University Chile Medical School, 1970. Professor honoris causa, Federal University Rio de Janeiro.
Assistant physical chemistry, University of Wisconsin, 1929-1931;
National Research Council fellow in biological science, 1931-1933;
investigator, Rockefeller Foundation, 1934;
investigator charge radiation work, National Research Council project, Wisconsin, 1934-1937;
associate biophysicist, Washington Biophysics Institute, National Institutes of Health, United States Public Health Service, 1937-1938;
biophysicist, Washington Biophysics Institute, National Institutes of Health, United States Public Health Service, 1938-1941;
senior biophysicist, Washington Biophysics Institute, National Institutes of Health, United States Public Health Service, 1941-1945;
principal biophysicist, Washington Biophysics Institute, National Institutes of Health, United States Public Health Service, 1945-1946;
head biophysicist, Washington Biophysics Institute, National Institutes of Health, United States Public Health Service, 1946-1950;
director biological division, Oak Ridge National Laboratory, 1946-1966;
senior research adviser, Oak Ridge National Laboratory, 1967-1973;
professor radiation biology, U. Tennessee, 1957-1966;
professor biomedical science, U. Tennessee-Oak Ridge Graduate School biomedical Sciences, 1966-1986;
director, Archives Radiation Biology, U. Tennessee, 1966-1986. Messenger lecturer Cornell Univercity, 1962. Consultant Oak Ridge National Laboratory, Brookhaven National Laboratory, National Institute for Environmental Health Sciences, National Cancer Institute, Plenum Public Company.
Consultant Environmental Protection Agency. Organizer foreign and domestic workshops and training courses in environmental mutagenesis and carcinogenesis. Civilianwith Atomic Energy Commission, Office of Scientific Research and Development, Office Surgeon General, United States Navy.
Member committee radiation biology, member committee photobiology, division biological and agriculture, chairman and member subcommittee radiobiology, division physical science National Research Council. Honorary president 9th International Photobiology Congress.
(William C. Taylor Department of Genetics University of Ca...)
(Delbert M. Shankel Departments of }1icrobiology and Bioch...)
Fellow American Association for the Advancement of Science, American Academy Arts and Science, Indian National Science Academy (foreign), Brazilian Academy of Sciences (foreign). Member Solar Energy Society, American Physiological Society, Radiation Research Society (president 1954-1955), American Society Cell Biology, International Association Radiation Research (president 1962-1966), National Association de Photobiologie (president 1954-1960, honorary president 1964, executive committee 1960-1966), Genetics Society of America (citation 1979), American Society Naturalists (vice president 1952-1953), Society General Physiologists, United States National Academy of Sciences (award for environmental quality 1979), American Society Microbiology, American Physiological Society, Environmental Mutagen Society (president 1969-1971), International Environmental Mutagens Society (president 1973-1977), Knoxville Academy Medicine (honorary).
Married Henrietta Wahlert, October 10, 1925.