Career
Born in Weferlingen, she was the fourth of five children born from the marriage of George Frederick Charles, Margrave of Brandenburg-Bayreuth and Princess Dorothea of Schleswig-Holstein-Sonderburg-Beck. In 1716 her mother was convicted of adultery and imprisoned. She probably never saw her again.
They had four children:
Charles Augustus Eugen, Hereditary Prince of Saxe-Weimar (Weimar, 1 January 1735 - Weimar, 13 September 1736).
Ernest Augustus II Konstantin, Duke of Saxe-Weimar-Eisenach (Weimar, 2 June 1737 - Weimar, 28 May 1758). Ernestine Auguste Sophie (Weimar, 4 January 1740 - Hildburghausen, 10 June 1786), married on 1 July 1758 to Ernst Frederick III Karl, Duke of Saxe-Hildburghausen.
Ernest Adolph Felix (born and died Weimar, 23 January 1741 / b Weimar, 1742 - d Weimar, 1743). Sophie Charlotte died in Ilmenau aged 33.
She was buried there.