Background
Ayscough was the son of Sir Edward Ayscough of South Kelsey and his wife Isabel Bolles, daughter of Sir John Bolles, 1st Baronet of Scampton, Lincolnshire.
Ayscough was the son of Sir Edward Ayscough of South Kelsey and his wife Isabel Bolles, daughter of Sir John Bolles, 1st Baronet of Scampton, Lincolnshire.
He was educated at Melton, Lincolnshire and admitted at Sidney Sussex College, Cambridge in 1667. He studied further in Padua in 1671 and entered Grey"s Inn in 1671, He was knighted on 17 January 1672.
He was baptised on 19 November 1650. In 1668 he succeeded to the family estates on the death of his father. He was twice appointed Sheriff of Lincolnshire in 1683 and 1684.
He was high steward of Great Grimsby from 1686 to October 1688 and commissioner for prizes from 1689 to June 1699.
In 1690 he was commissioner for drowned lands. Ayscough died at the age of about 49 at Grasby, Lincolnshire, and was buried at Stallingborough.
In 1685, he was elected Member of Parliament for Great Grimsby.