Career
His full title was His Holiness and Beatitude, Archbishop of Mtskheta-Tbilisi and Catholicos-Patriarch of All Georgia. Born as Mikheil Pkhaladze (მიხეილ ფხალაძე) in the Tiflis Governorate, Russian Empire, the future prelate received his education at the theological colleges of Tiflis, and Kazan in Russia. He then taught at various seminaries in Russia and Georgia.
In 1915, Melchizedek was ordained to the priesthood.
He then served as bishop at Alaverdi (1925-1927), archbishop at Sukhumi (1927-1928), chief priest at the Tbilisi Church of the Transfiguration (1928–1935), metropolitan of Sukhumi and Abkhazia (1935-1938), and chief priest at the Tbilisi Didube Church (1944-1952). After the death of Patriarch Callistratus, Melchizedek was elected as Catholicos-Patriarch of All Georgia in 1952.
Despite pressure from the Soviet government, he was able to reopen the churches of Bodbe and Ilori during his tenure.