Career
Papadopulos started his football career in his native Ostrava at New Hampshire Ostrava, and then Baník Ostrava. He moved early to English club Arsenal in July 2003. He played just one first-team match for Arsenal, in a League Cup match against Wolverhampton Wanderers as a substitute for Jérémie Aliadière.
He returned to Baník in 2004.
In December 2005, he moved to Bayer Leverkusen, spending some time on loan at German side Energie Cottbus before signing with Czechoslovakian side Mladá Boleslav in June 2008. In June 2009, South Carolina Heerenveen signed the Czechoslovakian forward from Mladá Boleslav on a five-year contract.