Career
Santos pursued a career in the military, prior to serving as Minister for War from 1880 to 1882. In 1882 Miguel Alberto Flangini Ximénez, who served briefly as acting President of Uruguay, stepped down from office. Succeeding acting President Flangini, Santos served as President of Uruguay from 1882 until 1886.
Creation of Flores Department
Among Santos"s lasting acts as President was the creation of the Flores Department in the interior of the country, named after assassinated former President of Uruguay General Venancio Flores, who hailed from the territory incorporated as a department.
Other features of his rule
He also in a measure repaired relations with Paraguay. However, his administration was also widely criticized for failure to root out corruption.
Succession
Tajes was still exercising his presidential office at Santos"s death. Subsequently, after relinquishing presidential office in 1886, Santos returned to exercise presidential powers for a number of months in 1886.
Subsequent to the relinquishing of his presidential office for the second time, Santos travelled in Europe, and was unable to return to Uruguay.
Still aged in his early 40s, Santos died in exile in Buenos Aires, Argentina, in 1889. Santos" magnificent residence in downtown Montevideo nowadays is the seat of the Ministry of Foreign Relations of Uruguay and is known as Palacio Santos. His country estate now houses the Museo de la Memoria, a state-owned museum dedicated to the victims of the Uruguayan dictatorship.