Career
She is a graduate of Barnstable High School. Frangione debuted on soap operas in 1977, playing the role of Tara Martin on All My Children. Frangione departed that role in 1979.
She is best known for her role as the scheming villainess Cecile DePoulignac on Another World, which she played from June 1981 to November 1984 winning the 1st Soap Opera Digest Awards as Outstanding Villainess in 1984.
She reprised the role four times, in 1986, 1989, 1993, and from October 1995 to June 1996.