Education
Harvard Medical School. Princeton University.
Harvard Medical School. Princeton University.
In 1996, after the discovery of the BRCA2 gene, Offit and his research group successfully identified the most common mutation on the gene associated with breast and ovarian cancer among individuals of Ashkenazi Jewish ancestry. Offit"s group would go on to discover or describe recurrent mutations causing increased risk for colon and prostate cancer, and, in 2013 and 2015, they described two genetic syndromes of inherited childhood lymphoblastic leukemia. Offit was honored for his contributions to the prevention and management of cancer with the 2013 American Society of Clinical Oncology-American Cancer Society Award and Lecture.
Offit was born in New York City on February 19, 1955 to Sidney Offit and Doctor Avodah K. Offit (née Komito).
Offit attended the Browning School and then Princeton University, where he was chairman of Tiger Magazine and later elected to the University Board of Trustees. After graduating magna cum laude from Princeton in 1977, he completed both an Doctor of Medicine at Harvard Medical School and an Master of Public Health at the Harvard School of Public Health.
In 1984, Offit married Emily Sonnenblick. Sonnenblick is a radiologist at Mount Sinai Hospital and the daughter of cardiologist Edmund Sonnenblick.
He is currently Chief of the Clinical Genetics Service at Memorial Sloan Kettering Cancer Center, a member of the Program in Cancer Biology and Genetics at the Sloan-Kettering Institute, and Professor of Medicine and Healthcare Policy and at Weill Cornell Medical College. He is also a member of both the Board of Scientific Counselors of the National Cancer Institute and the Evaluation of Genomic Applications in Practice and Prevention working group of the United States. Centers for Disease Control.