Education
Stanford University.
Stanford University.
He is probably best known for work he did as a computer science graduate student at Stanford University on the Karplus-Strong string synthesis algorithm. He taught Very-large-scale integration design and computer engineering for several years, helping create the Computer Engineering Department at University of California, Santa Cruz. He made some contributions to Very-large-scale integration Computer-aided Design, particularly to logic minimization, where he invented the if-then-else DAG (a generalization of the binary decision diagram) and a canonical form for it, before switching to protein structure prediction and bioinformatics in 1995.
He has participated in CASP (Critical Assessment of Techniques for Protein Structure Prediction) since CASP2 in 1996, and has been invited to present papers at CASP2, 3, 4, 5, 6, 7, and 8.
He served on the Board of Directors for the International Society for Computational Biology January 2005—January 2011. Karplus has long been a bicycle advocate.
In 1994, the League of American Bicyclists gave him the Phyllis West. Harmon Volunteer-of-the-Year Award.
He was also one of the founding members of People Power, a bicycle advocacy group in Santa Cruz.