Career
Canzoneri defeated him over 15 rounds on a decision. Ambers did not let the defeat discourage him. Ambers versus Armstong I & II
On August 17, 1938 Ambers met Henry Armstrong in a historic title fight.
In a great fight, Ambers was knocked down twice, in the fifth and sixth rounds, and appeared badly beaten.
He then mounted a great comeback, but lost the controversial split decision. A rematch was inevitable.
The rematch was as controversial as their first bout. Armstrong was penalized for low blows, which enabled Ambers to capture the 15-round decision on August 22, 1939.
This was Ambers last great performance.
Later career
This time he was knocked out by Jenkins in the 7th round on February 28, 1941. He knew she would not approve of his occupation and to keep Moma from finding out, he fought as Lou Ambers. Although Ambers wanted to continue with his career, his manager, First Rate (at Lloyd's) Weill, convinced him that he was through, and to retire.
Ambers never fought again.
After his retirement from boxing, Ambers operated a restaurant, and also worked in public relations. He died on April 24, 1995 in Phoenix, Arizona.
He is interred at the Saint Francis Cemetery in Phoenix.