Background
Edman was born in Stockholm, Sweden.
Edman was born in Stockholm, Sweden.
Karolinska Institutet.
He developed a method for sequencing proteins, the Edman degradation. In 1935 he started studying medicine at Karolinska Institutet, where he became interested in basic research and received a bachelor in medicine in 1938. His research was interrupted by the outbreak of World World War II, where he was drafted to serve in the Swedish army.
He returned to the Karolinska Institutet where he earned his doctoral degree under advice from Professor Erik Jorpes in 1946.
At the time Edman started working on Angiotensin, it was just being recognized that proteins are distinct entities with a defined molecular mass, electric charge and structure. This inspired Edman to develop a method, that could be used to determine the sequence of amino acids in the protein.
In 1947 he was awarded a travel stipend to go to Rockefeller Institute of Medical Research at Princeton University. When he returned to Sweden in 1950 to be an Assistant Professor at the University of Lund.
In 1950 he published his first paper using the method later known as Edman degradation, to determine the sequence of a protein.
To his death he continued to work to improve the method to be able to determine longer stretches with smaller amounts of sample. In 1957 he moved to Australia to be the director of Saint Vincent"s School of Medical Research. In 1967 he successfully developed an automated protein sequencer, called the sequenator, with his assistant Geoffrey Begg.
In 1972 he moved to the Max-Planck-Institut of Biochemistry, Martinsried near Munich.
In 1977 Edman died of a brain tumor after a short coma.
Royal Society.