Career
After the fall of Constantinople he was taken to the Peloponnese and to Crete. When still quite young he came to Venice, where Bessarion became his patron, and sent him to learn Latin at Padua. On the death of Bessarion, Lorenzo de" Medici welcomed him to Florence, where Lascaris gave Greek lectures on Thucydides, Demosthenes, Sophocles, and the Greek Anthology.
Lorenzo sent him twice to Greece in quest of manuscripts.
When he returned the second time (1492) he brought back about two hundred from Mount Athos. Meanwhile, Lorenzo had died.
He resided at Rome under Leo X, the first pope of the Medici family, from 1513 to 1518, returned under Clement VII in 1523, and Paul III in 1534. In the meantime he had assisted Louis XII in forming the library of Blois, and when Francis I had it removed to Fontainebleau, Lascaris and Budé had charge of its organization.
We owe to him a number of editiones principes, among them the Anthologia Graeca (1494), four plays of Euripides, Callimachus (about 1495), Apollonius Rhodius, Lucian (1496), printed in Florence in Greek capitals with accents, the scholia of Didymas (Rome 1517) and of Porphyrius (1518) on Homer (Rome 1518), and the scholia vetera on Sophocles (Rome 1518).
Among his pupils were Marco Musuro and Germain de Brie.