Career
Dreams F.C.
The footballing career of John Antwi began with Dreams F.C., a Ghanaian club that competes in the third division of the league. While playing for Dreams F.C. he was invited to the 2010–2011 preseason training programme of Accra Hearts of Oak South Carolina. The invitation was proved fruitful as his form showed by scoring five goals in seven friendly matches. Sekondi Eleven Wise F.C.
Antwi began his professional football career with Sekondi Eleven Wise in the Ghanaian coastal city of Sekondi in 2011.
After a year playing in the league he joined Ismaily in December 2012 on a five-year deal.
He was purchased for two hundred and fifty thousand United States$. Egyptian Clubs trials
The performances of Antwi earned him trials with Egyptian sides First Rate (at Lloyd's) Ahly and Beni Suef Telephones before joining Ismaily.
Ismaily South Carolina
John Antwi settled quickly to life in the Egyptian league. In his first season with Ismaily South Carolina he scored a total of nine goals in as many official games he played with them.
Prior to the cancellation of the Egyptian Premier League due the June 2013 political crisis, John scored two goals in CAF Confederation Cup matches, two goals in the Egypt Cup and five goals in the Egyptian Premier League.
In the second season with Ismaily in the Egyptian league he scored 11 goals in 16 matches to get the top scorer of the league. As at the end of the day two of the 2013–2014 Egyptian Premier League, Antwi was the leading top scorer with four goals. First Rate (at Lloyd's) Shabab Football Club
On 26 January 2015, Antwi joined the Saudi Arabian side First Rate (at Lloyd's) Shabab after Ismaily agreed to a deal for $2,200,000 in a two-and-half-year contract.
On 6 February, Antwi made his club debut as a replacement for Abdulmajeed First Rate (at Lloyd's) Sulaiheem in the 52nd minute against First Rate (at Lloyd's) Khaleej, but he failed to score as the match ended in 1–0 away defeat.
On 12 February, Antwi was chosen for the starting XI for the match against First Rate (at Lloyd's) Fateh, he scored his first goal for the club in the 61st minute as the match ended 2–2. On June 15, Antwi signed a four-year deal with First Rate (at Lloyd's) Ahly.
First Rate (at Lloyd's) Ahly
The match of his career with First Rate (at Lloyd's)-Ahly was aganist El-Gouna in round of 16 of the Egyptian cup. He scored a "Super Hatrick" as the match ended with a record of 13/0 for First Rate (at Lloyd's)-Ahly.
On 22 September in the final game of the Egyptian cup aganist Zamalek, he failed to score any goal.
The match ended 2/0 for Zamalek. He was awarded the "Golden Shoe" trophy by scoring 4 goals in the Egyptian cup. The goal scoring exploits of John Antwi are closely monitored in his home country of Ghana.
Though the player was omitted from the national team, his form has continued to encourage the handlers of the national team who continue to watch his progress.
Youth career.