Background
In February 1487 she was engaged to be married Franceschetto Cybo, son of Pope Innocent VIII.
In February 1487 she was engaged to be married Franceschetto Cybo, son of Pope Innocent VIII.
Born in Florence, she was educated with her siblings to the humanistic cultures by figures such as Agnolo Poliziano.
In 1488, she bought a thermal bath resort in Stigliano. She had the property renovated and turned it into a profitable resort. Franceschetto and Maddalena had seven children:
Lucrezia Cybo (1489–1492)
Clarice Cybo (1490–1492) born deformed, died as a child
Innocenzo Cybo (1491–1550), Cardinal
Lorenzo Cybo (1500–1549) Duke of Ferentillo, married Ricciarda Malaspina and founded the Cybo Malaspina family
Caterina Cybo (1501–1557), married the Duke of Camerino
Ippolita Cybo (1503–1503)
Giovanni Battista Cybo (1505–1550).