Career
Kalekas was a disciple of Demetrios Kydones. He lived in Italy, Crete and Lesbos where he translated the works of Boethius and Anselm of Canterbury into Greek, and several Latin liturgical Texts such as the Missa Ambrosiana in Nativitate Domini. Kalekas translated the Comma Johanneum into Greek from the Vulgate.
Kalekas was a unionist who sought to reconcile the Eastern and Western Churches.
In 1390, he wrote a work castigating the Byzantines for their separation from the Western Church. As a result, he was forced to seek refuge with the Dominicans at Mytilene, where he died in 1410.