École nationale supérieure des Beaux-Arts.
After his initial training in an architectural workshop, he entered the studio of Charles-Auguste Questel at the École Nationale Supérieure des Beaux-Arts while also working for various architects, including Charles Garnier. He was in residence at the Villa Medici 1878-1881. In 1882 Nénot began his career, during which he was appointed architect of the Sorbonne, which remains his great work, as well as designing other university buildings in Paris and a number of private residential and commercial buildings.
In 1895 he was elected department chair for architecture in the Académie des beaux-arts
His last position was Director General for the architecture of the Palace of Nations in Geneva, where he died in an accident.