Career
He was a research professor at the University at Buffalo and served as chief of dermatology at the Roswell Park Cancer Institute. Klein developed a technique that allowed the separation of whole human blood into its component parts of plasma, platelets, white blood cells, and red blood cells, greatly increasing the efficiency of the entire transfusion process. Now three people could benefit from a single donor instead of one, with red blood cells used for anemic individuals, platelets for cancer patients, and plasma for those with decreased blood volume.
Klein"s results were published in both the New England Journal of Medicine and the Journal of Pediatrics and earned him the first prize for originality of research from the International Society for Hematology in 1956.