Career
Brescia
Born in Trescore Balneario, Lombardy, Defendi started his career at Lombard side Brescia. Defendi spent 3 seasons on loan to various Lega Pro clubs from 2011 to 2014. Como
On 18 June 2014 Como bought 50% registration rights from Brescia.
Defendi scored 7 goals in the first edition of Lega Pro Unica Divisione plus 1 goal in semi-final match against Matera.
Return to Brescia
In June 2015 both club failed to form a deal for the price of the player, which Brescia bought back the 50% registration rights by submitting a higher bid to Lega Serie B, the mediator. Defendi wore no.21 shirt for Brescia in 2015-2016 Serie B. However, on 26 August Defendi was signed by Arezzo in a temporary deal.