Career
Jokisch was drafted by the Cleveland Indians in the 39th round of the 2007 Major League Baseball Draft out of Virginia High School in Virginia, Illinois, but did not sign and played college baseball at Northwestern University. He was then drafted by the Chicago Cubs in the 11th round of the 2010 Major League Baseball Draft and signed. In 2013, while pitching for the Tennessee Smokies, he pitched a no-hitter.
Jokisch was called up to the majors for the first time on September 2, 2014.