Career
He played parts of three seasons in Major League Baseball for the Baltimore Orioles in 1957-1958 and 1961. He entered the American League at age 17. In 1957, Zupo, who was nicknamed "Noodles", entered the league as a 17-year-old rookie without having played in the minor leagues.
That season, together with George Zuverink, Zupo twice formed the only "Z" battery in Major League history, the first time coming on July 1, 1957 when Zupo made his big-league debut with a 10th-inning catching appearance against the New York Yankees.
Zupo held many different jobs including a fishing guide, business owner, and wholesale leather proprietor.