Career
Françoise had an older brother, Leonor, Duke of Longueville, Duke of Estouteville, and Prince du Sang (1540–1573), who married, in 1563, Marie d'Estouteville (1539–1601), by whom he had issue, including Henri I, himself later Duke of Longueville. Françoise was born on 5 April 1549 in Châteaudun, France. She was the only daughter of François d'Orléans, Marquis of Rothelin, Prince of Chalet-Aillon, Viscount of Melun, and Jacqueline de Rohan, herself the Marquise of Rothelin in her own right.
Her father had died on 25 October 1548, less than six months before her birth. From birth she was known as Mademoiselle de Longueville. Françoise was left a widow shortly before her 20th birthday, and she chose not to remarry.
Françoise died in Paris on 11 June 1601 at the age of 52, and was buried at Gaillon. Charles, Count of Soissons (3 November 1566 – 1 November 1612) married Anne de Montafié (1577–1644) and had issue. Louis de Bourbon (1567–1569) died in infancy.
Benjamin de Bourbon (1569–1573) died in infancy.