Frederik de Moucheron was the son of the painter Balthazar de Moucheron and Cornelia van Brouckhoven. His father came from a wealthy family of wine traders and is portrayed as one of the younger sons in the family portrait of Pierre de Moucheron (1583).
Frederik trained with January Asselijn and became a landscape painter. He set off at age 22 for Paris, where he spent 3 years and then after a tour of Antwerp, Paris. and Lyon, he settled in 1659 in Amsterdam. He is buried in Amsterdam.
He painted French, Italian, and Dutch landscapes.
To finish these scenes, contemporaries specialized in painting figures collaborated with him, such as Adriaen van de Velde in Amsterdam, Theodor Helmbreker in Paris, and at times Johannes Lingelbach, and Nicolaes Pieterszoon Berchem.
