Career
He would play for the Saint Louis Cardinals, San Francisco Giants, and Boston Red Sox. In his playing days, he stood 6"1" (854 cm) tall, weighed 198 pounds (898 kg), and threw and batted right-handed. He was born in Hammond, Indiana.
Muffett came to the major leagues with Saint Louis in 1957 and fashioned his best overall season, winning three of five decisions, posting an earned run average of 2.25 and notching eight saves.
After retiring as a player, Muffett was a longtime MLB pitching coach for the Cardinals, California Angels and Detroit Tigers between 1967 and 1994. He survived a bout with cancer in 1987, but continued in his role as Tiger pitching coach during his recovery.
Billy Muffett died June 15, 2008 at his home in Monroe, Louisiana.