Career
Guckelsberger worked in a pharmacy in Stuttgart, but started studying chemistry with Hermann von Fehling, also in Stuttgart, for two semesters. With the recommendation of Fehling, Guckelsberger joined the laboratory of Justus von Liebig at the University of Gießen, where he received his Doctor of Philosophy His research there concerned the oxidation of albumin and related compounds. In the 1850s he started working at a paper factory near Großalmerode, which he became technical director of.
Later he directed a soda factory.
Some sources cr him with significant improvements to the manufacture of soda, while others dispute the claim, giving more of the cr to his assistant Ludwig Mond. Guckelberger retired in 1867 and lived near Kassel the rest of his life.