Career
He served in the first council of the Political Bureau of the First Republic of Guinea as Minister of Finance from 1957. In this role, he signed the first bank notes of the republic. Drame was made responsible for the plans for economic development of Guinea for the periods 1960-1963, 1964–1971 and 1973-1979.
He also served as an ambassador to Ivory Coast.
Dramé was Minister of Planning when he was arrested on the night of 18/19 July 1976 and imprisoned at Camp Boiro. At a press conference on 2 August 1976, Sekou Toure announced the arrest in Conakry of Dramé and several other alleged plotters, including Telli Diallo, Alpha Oumar Barry and Lamine Kouyaté.
On 15 February 1977, Dramé was place on the "black diet": no food and no water. He died on 1 March 1977.