Career
Her first husband was Hendrik van Brederode, who played an important part in the events leading up to the Eighty Years" War. After he became one of the leaders in the resistance against the Spanish Inquisition and Spanish rule in the Netherlands, she helped him collect funds. This is because she was in charge of Anna"s household at the time.
Frederick died in 1576.
In 1589 she inherited Limburg from Adolf, her half-brother. Alpen was occupied by the Dutch Republic in 1597 and the following year by Spanish forces.