Career
Markopoulos played basketball with the Greek clubs Olympos Saranta Ekklision and Dimokritos. Markopoulos has coached, in his career, teams such as: Iraklis, PAOK, Aris, Makedonikos, AEK Athens, and Maroussi. His most remarkable success was the acquisition of the Korać Cup championship, while with PAOK in 1993-1994.
He was also named the Greek League coach of the Year in 2014.
In the summer of 2014, he extended his contract with PAOK through the 2018-2019 season.