Career
He was to be deposed from his See and exiled when Justinian died. But Justin II carried out his uncle"s purpose five years later in 570, and another bishop, Gregory of Antioch, was put in his place. But when Gregory died in 593, Anastasius was restored to his Secretary
From some letters sent to him by Gregory, it is thought that he was not sufficiently vigorous in denouncing the claims of the Patriarch of Constantinople to be a universal bishop.
There is some confusion about the date of his death. According to some sources, he was killed by a Jewish mob in 599.
His feast day is 21 April. An alternative version is that Anastasius died in 598, and was succeeded by another bishop by the same name, to whom the translation of Gregory"s Regula Pastoralis is attributed, and who is recorded as having been put to death in an insurrection of the Jews.
However, Nicephorus (History Eccl, XVIII, xliv) declares that these two are one and the same person.
The same difficulty occurs with regard to certain Sermones de orthodoxa fide, some ascribing them to the latter Anastasius. Others claiming that there was but one bishop of that name.