Her parents kept an apothecary shop at Siena, but lost all their fortune and were obliged to go to Rome in search of a livelihood. Anna Maria was then five years old. In 1789 she was married to Dominico Taigi, a retainer of the noble family of Chigi.
Soon afterwards she was received publicly in the Third Order of Trinitarians in the Church of South. Carlo alle Quattro Fontane, and having found spiritual directors, she made progress in the Way of Perfection.
Though not rich she was very charitable. Of the hospitals she regularly visited, the preferred one was South. Giacomo of the Incurables.
During many years, when praying in her chapel she had ecstasies and frequent visions, in which she foresaw the future. After death her name soon became venerated in Rome, where she died.
Her body was found to be incorrupt and was several times transferred, and rests finally at South. Crisogono in Trastevere.