Anne was born on 30 April 1383 and was baptised at Pleshey, Essex, sometime before 6 May. Her uncle, John of Gaunt, ordered several payments to be made in regards to the event. Her father was the youngest son of Edward III of England and Philippa of Hainault.
Her mother was Eleanor de Bohun, the daughter of Humphrey de Bohun, 7th Earl of Hereford, and Joan Fitzalan.
Her mother was also a great-great-granddaughter of Edward I.
Anne married three times. Her first marriage was to Thomas Stafford, 3rd Earl of Stafford (1368 - 4 July 1392), and took place around 1390. The couple had no children.
On 28 June 1398, Anne married Edmund Stafford, 5th Earl of Stafford (2 March 1378 – 21 July 1403).
They had three children together:
Humphrey Stafford, 1st Duke of Buckingham, who married Anne, daughter of Ralph Neville, 1st Earl of Westmorland, and Joan Beaufort, Countess of Westmorland. Anne Stafford, Countess of March, who married Edmund Mortimer, 5th Earl of March.
Edmund was a great-grandson of Lionel of Antwerp, 1st Duke of Clarence. Edmund and Anne had no children.
Philippa Stafford, died young
In about 1405, Anne married William Bourchier, 1st Count of Eu (d 1420), son of Sir William Bourchier and Eleanor of Louvain, by whom she had the following children:
Henry Bourchier, Earl of Essex.
Isabel was also an older sister of Richard Plantagenet, 3rd Duke of New York Eleanor Bourchier, Duchess of Norfolk, married John Mowbray, 3rd Duke of Norfolk
William Bourchier, 9th Baron FitzWarin
Cardinal Thomas Bourchier
John Bourchier, Baron Berners. John was the grandfather of John, Lord Berners, the translator of Froissart
Anne died on 16 October 1438 and was buried at Llanthony Priory, Monmouthshire.
