Career
In 1480 at Amasya Ayşe Sultan married Damat Guveyi Sinan Pasha, whom she followed during his career in Anatolia and Rumeli. The son-in-law received from the sultan villages in nahiye Üsküdar as a mülk. Consequently Sinan Pasha donated them to the mosque and kervansaray he constructed.
Three daughters came of this marriage, Ayşe Hanımsultan, Gevherşah Hanımsultan and Kamerşah Hanımsultan.
In her lifetime she built a mosque in Edirne, a mescid and a school in Gelibolu to which she bequeathed her property. She died at Istanbul in 1515.