Background
Hansch, Corwin Herman was born on October 6, 1918 in Kenmare, North Dakota, United States. Son of Herman William and Rachel (Corwine) Hansch.
chemist pharmacist Pharmacologist
Hansch, Corwin Herman was born on October 6, 1918 in Kenmare, North Dakota, United States. Son of Herman William and Rachel (Corwine) Hansch.
Bachelor of Science, University Illinois, 1940. Doctor of Philosophy, New York University, 1944. Degree (honorary), University Torino, 2004.
He became known as the "father of computer-assisted molecule design."
Hansch taught Organic Chemistry for many years at Pomona College, and was known for giving complex lectures without using notes. His course in Physical Biology-Organic Medicinal Chemistry was ground-breaking at an undergraduate level Hansch may be best known as the father of the concept of quantitative structure-activity relationship (Quantitative structure–activity relationship), the quantitative correlation of the physicochemical properties of molecules with their biological activities.
He is also noted for the Hansch equation, which is used in
Multivariate Statistics - Multivariate statistics is a set of statistical tools to analyse data (eg, chemical and biological) matrices using regression and/or pattern recognition techniques.
Hansch Analysis - Hansch analysis is the investigation of the quantitative relationship between the biological activity of a series of compounds and their physicochemical substituent or global parameters representing hydrophobic, electronic, steric and other effects using multiple regression correlation methodology. Hansch-Fujita constant - The Hansch-Fujita constant describes the contribution of a substituent to the lipophilicity of a compound.
Research Interests: Organic Chemistry. Interaction of organic chemicals with living organisms, Quantitative Structure Activity Relationships (Quantitative structure–activity relationship).
Fragment based regression analysis for quantitative structure-activity relationship (Hansch-analysis)
He died of pneumonia on May 8, 2011 in Claremont, California at 92.
Fellow Royal Society Chemistry (London, honorary). Member L'Istituto Lombardo Accademiadi Scienze E Letters (Milan, honorary), L'Istituto Lombardo (honorary), Italian Society Pharmaceutical Science (honorary), American Chemical Society (Medicinal Chemistry Hall of Fame, 2007).
Married Gloria J. Tomasulo, January 8, 1944. Children— Clifford, Carol.