Background
Ganellin, Charon Robin was born on January 25, 1934 in London. Son of Leon and Beila (Cluer) Ganellin.
( Medicinal chemistry is a complex topic. Written in an e...)
Medicinal chemistry is a complex topic. Written in an easy to follow and conversational style, Basic Concepts in Medicinal Chemistry focuses on the fundamental concepts that govern the discipline of medicinal chemistry as well as how and why these concepts are essential to therapeutic decisions. The book emphasizes functional group analysis and the basics of drug structure evaluation. In a systematic fashion, learn how to identify and evaluate the functional groups that comprise the structure of a drug molecule and their influences on solubility, absorption, acid/base character, binding interactions, and stereochemical orientation. Relevant Phase I and Phase II metabolic transformations are also discussed for each functional group. Key features include: • Discussions on the roles and characteristics of organic functional groups, including the identification of acidic and basic functional groups. • How to solve problems involving pH, pKa, and ionization; salts and solubility; drug binding interactions; stereochemistry; and drug metabolism. • Numerous examples and expanded discussions for complex concepts. • Therapeutic examples that link the importance of medicinal chemistry to pharmacy and healthcare practice. • An overview of structure activity relationships (SARs) and concepts that govern drug design. • Review questions and practice problems at the end of each chapter that allow readers to test their understanding, with the answers provided in an appendix. Whether you are just starting your education toward a career in a healthcare field or need to brush up on your organic chemistry concepts, this book is here to help you navigate medicinal chemistry. About the Authors Marc W. Harrold, BS, Pharm, PhD, is Professor of Medicinal Chemistry at the Mylan School of Pharmacy, Duquesne University, Pittsburgh, PA. Professor Harrold is the 2011 winner of the Omicron Delta Kappa "Teacher of the Year" award at Duquesne University. He is also the two-time winner of the "TOPS" (Teacher of the Pharmacy School) award at the Mylan School of Pharmacy. Robin M. Zavod, PhD, is Associate Professor for Pharmaceutical Sciences at the Chicago College of Pharmacy, Midwestern University, Downers Grove, IL, where she was awarded the 2012 Outstanding Faculty of the Year award. Professor Zavod also serves on the adjunct faculty for Elmhurst College and the Illinois Institute of Technology. She currently serves as Editor-in-Chief of the journal Currents in Pharmacy Teaching and Learning.
http://www.amazon.com/gp/product/1585282669/?tag=2022091-20
(This book provides the ultimate resource for medicinal an...)
This book provides the ultimate resource for medicinal and pharmaceutical chemists, presenting concise chemical, physical, and bibliographic data on drugs and pharmacological agents. More than 30,000 compounds are contained in 8,200 entries. Coverage includes all currently marketed drugs, pharmacological tools, bioactive natural products, and compounds in the later stages of clinical trials. The types of data provided include • entry names • synonyms indicating generic names, trade names, and company codes • accurately drawn diagrams depicting stereochemistry • approved names • trade names • molecular formulae and weight • physical properties, including melting point and/or boiling point • disassociation constant • partition coefficients - both experimental and calculated • hazard and toxicity data • patenting company • marketing/development status • therapeutic uses • mechanism of action • key literature citations • carefully selected bibliographies directing the reader straight to the primary literature Four detailed indexes help readers find exactly the information they need: Name (generic, chemical, trivial), Molecular Formula, and CAS Registry Number and Therapeutic Category (225 categories). Dictionary of Pharmacological Agents serves as the information source, comprehensively presenting essential information for medicinal chemists
http://www.amazon.com/gp/product/0412466309/?tag=2022091-20
(This indispensable handbook offers quick and convenient a...)
This indispensable handbook offers quick and convenient access to essential information on the wide range of drugs a dentist may use or prescribe in their management, indicating their use, dosage and possible interactions with other drugs that the patient may be receiving. Medical contraindications, and the importance of the underlying disease for which the drug is prescribed and its affect on dental management are explained. Drugs taken by out-patients which may be encountered in general dental practice and interactions with drugs contained in the Dental Practitioner's Formulary have been included. This essential handbook provides a quick reference for dental practitioners and students enabling them to assess the importance of drugs their patient may be receiving in relationship to dental management.
http://www.amazon.com/gp/product/0192632744/?tag=2022091-20
(Medicinal Chemistry has always been a tough course, a sou...)
Medicinal Chemistry has always been a tough course, a source of frustration in every school of pharmacy. Now ASHP has made both learning and teaching it much easier and more effective, with the publication of Medical Chemistry Self Assessment. Developed by Robin M. Zavod and Marc W. Harrold, authors of the highly praised textbook, Basic Concepts in Medicinal Chemistry, this Self Assessment is the only publication of its kind. A highly engaging way for pharmacy and pre-health students to master the complexities of medicinal chemistry, it reinforces what they learn in class with practice problems and review questions which are answered at the end of the book. The Self Assessment book and its related online content are also handy teaching tools, as well as a source of new problem formats and strategies for exploring concepts from different perspectives. Zavod and Harrold s approach provides a clear translation of organic chemistry concepts into medicinal chemistry language, and includes numerous clinically relevant examples, relating medicinal chemistry to therapeutic decisions. A valuable enhancement to any medicinal chemistry text, this book will also be very helpful for students learning organic or biochemistry, as well as for practitioners who want to renew their understanding of medicinal chemistry.
http://www.amazon.com/gp/product/1585284645/?tag=2022091-20
(This Second Edition covers exciting progress recently mad...)
This Second Edition covers exciting progress recently made with individual drugs and includes a special chapter on the impact of molecular biology on drug design. Other additions to the Second Edition include structure-activity relationships, the role of molecular biology in drug discovery, and drug access and prodrugs. Written for students considering a research career in drug development, this volume is conveniently divided into two parts. The first half introduces readers to the mechanisms of action of drugs and the approaches adopted in designing new drugs. The second half contains chapters written by the discoverers or developers of individual successful drugs who trace the history of the drugs to the present day.
http://www.amazon.com/gp/product/012274120X/?tag=2022091-20
chemist researcher medical educator
Ganellin, Charon Robin was born on January 25, 1934 in London. Son of Leon and Beila (Cluer) Ganellin.
Bachelor of Science in Chemistry, Queen Mary College, London, 1955. Doctor of Philosophy, Queen Mary College, London, 1958. Doctor of Science, London University, 1986.
Doctor of Science (honorary), Aston University, 1995.
Director of Histamine Research, Smith Kline and French Research Ltd. 1975-1980, Vice-President Research 1980-1984, Vice-President Chemical Research 1984-1986. Honorary Lecturer, Department, of Pharmacology, University College, London 1975-1986, Smith Kline and French Professor, of Medicinal Chemistry since 1986.
Honorary Professor, of Medicinal Chemistry, University of Kent since 1979.
(This indispensable handbook offers quick and convenient a...)
(This book provides the ultimate resource for medicinal an...)
(This Second Edition covers exciting progress recently mad...)
(Medicinal Chemistry has always been a tough course, a sou...)
( Medicinal chemistry is a complex topic. Written in an e...)
Fellow Royal Society, Royal Society Chemistry (medicinal chemistry medallion 1977, Tilden medal 1982, Adrian Albert medal 1999), Queen Mary Westfield College. Member American Chemical Society (Medicinal Chemistry award 1980, Hall of Fame Division Medicinal Chemistry 2007), Society for Chemical Industry (Messel medal 1988), Society for Drug Research (Drug Discovery award 1989), British Pharmaceutical Society, Society Española Chim. Therapeutica (honorary), Spanish Royal Academy Pharmacy (foreign correspondent adacemician 2006).
Married Tamara Greene, December 27, 1956 (deceased November 1997). Children Nicole Joanne, Mark David. Married Monique Lehmann Garbarg, July 2003.