Background
Choh Hao Li was born on April 21, 1913, in Guangzhou, China. He was the son of Kan-chi Li and Mewching Tsui. He was the fourth of eleven children in the family. Li came to the United States in 1935 and was naturalized in 1955.
22 Hankou Rd, Gulou Qu, Nanjing Shi, Jiangsu Sheng, China, 210008
In 1933 Li graduated as a Bachelor of Science from the University of Nanjing.
University of California, Berkeley, CA, United States
Li earned his Doctor of Philosophy in Organic Chemistry in 1938 from the University of California in Berkeley.
Choh Hao Li in the laboratory
Choh Hao Li in the laboratory
Choh Hao Li and Herbert McLean Evans
Choh Hao Li and Archer J.P. Martin
Choh Hao Li and Linus Pauling at the Gilbert Newton Lewis Medal ceremony
Choh Hao Li with researchers in the laboratory
Signed photo of Choh Hao Li
(Hormonal Proteins and Peptides, Volume II reviews extensi...)
Hormonal Proteins and Peptides, Volume II reviews extensively the knowledge on the biology and chemistry of the protein and peptide hormones. This book presents the structures of the various protein and peptide hormones. Organized into three chapters, this volume begins with an overview of the various aspects of the structure and function of adrenocorticotropin hormone (ACTH) with reference to the ability to stimulate the adrenal gland of the rat, amphibian melanophores, and adipose tissues of the rat and rabbit. This text then reviews the isolation, purification, and elucidation of the amino acid sequence of corticotropins from various species. Other chapters consider the structures of porcine and human ACTH. This book discusses as well the working hypothesis for studies on the secondary-tertiary structure of peptide hormones. The final chapter deals with the abbreviations used for amino acids and protecting groups. This book is a valuable resource for peptide chemists, biologists, biochemists, and research workers.
https://www.amazon.com/Hormonal-Proteins-Peptides-Choh-Hao-ebook/dp/B01M0174FQ/?tag=2022091-20
1973
(Hormonal Proteins and Peptides, Volume I reviews extensiv...)
Hormonal Proteins and Peptides, Volume I reviews extensively the knowledge on the biology and chemistry of the protein and peptide hormones. This book presents the structures of the various protein and peptide hormones. Organized into five chapters, this volume begins with an overview of the chemistry of several hormonal glycoproteins. This text then presents the research on the purification and chemistry of thyroid-stimulating hormone (TSH). Other chapters consider the study of ovine interstitial cell-stimulating hormone, and concentrate to some extent on the very closely related bovine species. This book discusses as well some aspects of the biology of the pituitary interstitial cell-stimulating hormone or luteinizing hormone in mammalian species. The final chapter deals with the correlation of the primary structure with function for a better understanding of the mechanism of action of the hormone at a molecular level. This book is a valuable resource for biologists, biochemists, and research workers.
https://www.amazon.com/Hormonal-Proteins-Peptides-Choh-Hao-ebook/dp/B01HGRF46E/?tag=2022091-20
1973
(Hormonal Proteins and Peptides, Volume V: Lipotropin and ...)
Hormonal Proteins and Peptides, Volume V: Lipotropin and Related Peptides deals with peptides that have neurobiological properties. This book consists of five chapters. Chapter 1 reviews the chemistry of melanotropins, while Chapter 2 describes the most potent morphinelike peptide, ?-endorphin. The third chapter summarizes the chemistry and biology of lipotropins that were discovered and characterized from 1964 to 1965. Chapter 4 examines the properties and physiological role of neurophysins. A historical perspective of the achievements of the Uppsala School regarding the separation methods and biographical sketch of Arne Tiselius are presented at the last chapter. This book is recommended for endocirnologists, clinicians, and students researching on lipotropins.
https://www.amazon.com/Lipotropin-Related-Peptides-Choh-Hao-ebook/dp/B01D4OEKY0/?tag=2022091-20
1978
李卓皓
Choh Hao Li was born on April 21, 1913, in Guangzhou, China. He was the son of Kan-chi Li and Mewching Tsui. He was the fourth of eleven children in the family. Li came to the United States in 1935 and was naturalized in 1955.
Li attended Pui-Ying Middle School in Canton, where he developed a curiosity about nature at an early age.
In 1933 Li graduated as a Bachelor of Science from the University of Nanjing before moving to the United States to attend graduate school at The University of California in Berkeley in 1935. Li earned his Doctor of Philosophy in Organic Chemistry in 1938.
From 1933 until the summer of 1935 Li was an instructor in chemistry in the University of Nanking and during these years he conducted research leading to his first scientific paper published in 1935. The same year he emigrated to the USA, where he took up postgraduate studies at the University of California at Berkeley and later joined the staff in 1938.
Li's first academic appointment was with the Institute of Experimental Biology under Herbert Evans. The anti-Asian sentiment was strong during the Depression, making jobs and housing difficult to find for the young scholar. Evans took an interest in Li and offered him a tiny workspace in the basement of his Experimental Biology Laboratory in the Life Sciences Building at Berkeley. There Li began to develop methods for isolating the anterior pituitary hormones in pure form. Li was either the first or among the first to isolate and identify the anterior pituitary hormones. The initial breakthrough came in 1940 when he isolated luteinizing hormone. ACTH was the first hormone to be chemically identified and partially synthesized. It took 32 years of research for Li to synthesize the human growth hormone. The identification, purification and later synthesis of human growth hormone and the identification of beta-endorphin were his two most widely recognized achievements. His last accomplishment was the identification and purification of insulin-like growth factor I.
Li served as Director of the Hormone Research Laboratory at Berkeley from 1950 to 1967 and at UCSF from 1967 until his retirement in 1983. He was succeeded as Director of the HRL by William Rutter. During his career, Li received many scientific awards and ten honorary degrees and published 1,100 scientific articles with over 300 collaborators. Leading figures in protein hormone chemistry and endocrinology worked in his laboratory as doctoral students, post-doctoral fellows, or visiting scientists. Among Li's many honors, the most notable was the Lasker Award for Basic Medical Research. Although he was nominated at least twice for the Nobel prize, this highest of scientific awards eluded him. Li headed the Laboratory of Molecular Endocrinology from 1983 until his death in 1987.
In more than 50 years of research in the University of California system, Li played a key role in the discovery of eight of the nine critical hormones produced by the pituitary gland, a pea-sized organ deep in the brain that regulates body growth, metabolism, and fertility.
(Hormonal Proteins and Peptides, Volume II reviews extensi...)
1973(Hormonal Proteins and Peptides, Volume I reviews extensiv...)
1973(Hormonal Proteins and Peptides, Volume V: Lipotropin and ...)
1978
Li grew up in Guangzhou, China, with ten siblings, all of whom became successful scholars. One brother, Choh Ming Li, played a key role in determining where Li's career would be lived out.
Li married a fellow chemistry student from Canton, Shen-hwai Lu (Annie) on October 1, 1938. She received her masters in Agricultural Economics from The University of California in Berkeley when their eldest child was two. Their son Dr. Wei-i Li is a surgeon in Bellevue, Washington; their artist daughter, Eva Li Hill, lives in Toronto; and veterinarian daughter, Dr. Ann-si Li, lives in Berkeley.