Background
Hynes, Richard Olding was born on November 29, 1944 in Nairobi, Kenya, Africa. Son of Hugh Bernard Noel and Mary Elizabeth Hynes.
(Fibronectins comprise a class of high molecular weight gl...)
Fibronectins comprise a class of high molecular weight glycoproteins present both in extracellular matrices and in soluble form in body fluids. Although they have been studied for about forty years, their real significance emerged only during the past decade. Intensive research has focused on their role in platelet function, cell migration, the cytoskeleton, reticuloendothelial function, and on alterations in fibronectin distribution during development and disease. Fibronectins have emerged as glycoproteins with a very interesting set of properties generally involving adhesion of cells to cells or to extracellular material. In more recent years, the complete sequences of several fibronectin molecules and their genes were determined, the relation between structure and function was understood and much has been learned about cell surface receptors for fibronectins and other adhesive ligands. Having been at the forefront of all these exciting developments, the author has synthesized the entire field and with all the latest information at hand for the first time given it a clear perspective.
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university professor molecular biologist
Hynes, Richard Olding was born on November 29, 1944 in Nairobi, Kenya, Africa. Son of Hugh Bernard Noel and Mary Elizabeth Hynes.
Hynes earned his Bachelor of Arts in 1966 and Master of Arts in 1970 from the University of Cambridge, both in biochemistry. He received his Doctor of Philosophy in biology from the Massachusetts Institute of Technology in 1971. He worked as a postdoctoral fellow at the Imperial Cancer Research Fund from 1971 to 1974.
His research focuses on cell adhesion and the interactions between cells and the extracellular matrix, with a particular interest in understanding molecular mechanisms of cancer metastasis. He is well known as a co-discoverer of fibronectin molecules, a discovery that has been listed by Thomson Reuters ScienceWatch as a Nobel Prize candidate. Hynes became a faculty member in the biology department at Massachusetts Institute of Technology in 1973 and was promoted to full professor in 1983.
He was awarded Howard Hughes Medical Institute Investigator status in 1988.
He served as the head of the biology department from 1989 to 1991 and as the director of the Massachusetts Institute of Technology Center for Cancer Research from 1991 to 2001, and became the Daniel K. Ludwig Professor for Cancer Research and affiliated with the Koch Institute in 1999. Hynes served as the president of the American Society for Cell Biology in 2000.
He has also published on public policy and participated in the development of United States research guidelines for stem cell research, particularly embryonic stem cells.
(Fibronectins comprise a class of high molecular weight gl...)
(Fibronectins comprise a class of high molecular weight gl...)
Royal Society; National Academy of Sciences]
Since 2004 he has been an associate member of the Broad Institute. He has been a member of the Board of Governors of the Wellcome Trust since 2007. He was elected a fellow of the American Academy of Arts and Sciences in 1987, a Fellow of the Royal Society in 1989, a member of the Institute of Medicine in 1995, and a member of the United States National Academy of Sciences in 1996.
Married Fleur Marshall, July 29, 1966. Children: Hugh Jonathan, Colin Anthony.